St18 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

St18
suppression of tumorigenicity 18
MGI:2446700

20 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lyz2^tm1(cre)Ifo/Lyz2⁺ St18^{tm1c(KOMP)Wtsi}/St18^{tm1c(KOMP)Wtsi} involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N	abnormal retina blood vessel morphology	J:298828
	diarrhea	J:298828
	normal homeostasis/metabolism phenotype	J:298828
	normal immune system phenotype	J:298828
	increased circulating interleukin-1 beta level	J:298828
	increased inflammatory response	J:298828
	increased susceptibility to induced morbidity/mortality	J:298828
	increased susceptibility to weight loss	J:298828
	increased vascular permeability	J:298828
	slow postnatal weight gain	J:298828
St18^{tm1a(KOMP)Wtsi}/St18^{tm1a(KOMP)Wtsi} C57BL/6N-St18^{tm1a(KOMP)Wtsi}/Wtsi	decreased body weight	J:175295
	decreased circulating alanine transaminase level	J:175295
	decreased circulating aspartate transaminase level	J:175295
	decreased circulating LDL cholesterol level	J:175295
	decreased circulating serum albumin level	J:175295
	decreased rib number	J:175295
	decreased total body fat amount	J:175295
	increased sacral vertebrae number	J:175295
St18^{tm1c(KOMP)Wtsi}/St18^{tm1c(KOMP)Wtsi} Tg(Vil1-cre)20Syr/0 involves: C57BL/6 * C57BL/6N * DBA/2	normal growth/size/body region phenotype	J:298828
	normal mortality/aging	J:298828

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24