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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Serac1
serine active site containing 1
MGI:2447813
35 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Serac1em1(IMPC)Tcp/Serac1em1(IMPC)Tcp
C57BL/6NCrl-Serac1em1(IMPC)Tcp/Tcp 		abnormal freezing behavior J:211773
abnormal ovary morphology J:211773
decreased exploration in new environment J:211773
decreased locomotor activity J:211773
decreased vertical activity J:211773
enhanced contextual conditioning behavior J:211773
enlarged lymph nodes J:211773
increased freezing behavior J:211773
Serac1em1Bcgen/Serac1em1Bcgen
C57BL/6N-Serac1em1Bcgen 		abnormal basal ganglion morphology J:326672
abnormal cellular respiration J:326672
abnormal hepatocyte morphology J:326672
abnormal liver morphology J:326672
abnormal mitochondrial fission J:326672
abnormal muscle fiber morphology J:326672
abnormal oxidative phosphorylation J:326672
aciduria J:326672
brain lesion J:326672
cardiomyopathy J:326672
decreased circulating cholesterol level J:326672
decreased grip strength J:326672
decreased heart left ventricle wall thickness J:326672
decreased hepatocyte mitochondrial DNA content J:326672
decreased mitochondrial DNA content J:326672
decreased mitochondrial size J:326672
decreased skeletal muscle fiber mitochondrial DNA content J:326672
encephalopathy J:326672
enlarged heart J:326672
impaired hearing J:326672
increased liver cholesterol level J:326672
increased liver glycogen level J:326672
increased liver triglyceride level J:326672
increased mitochondrial number J:326672
increased or absent threshold for auditory brainstem response J:326672
muscle weakness J:326672
normal reproductive system phenotype J:326672
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory