Nbeal2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nbeal2
neurobeachin-like 2
MGI:2448554

25 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nbeal2^gps/Nbeal2^gps 129S1/SvImJ-Nbeal2^gps	decreased neutrophil cell number	J:236370
	decreased platelet alpha-granule number	J:236370
	enhanced megakaryocyte emperipolesis	J:236370
	thrombocytopenia	J:236370
Nbeal2^{tm1a(EUCOMM)Wtsi}/Nbeal2^{tm1a(EUCOMM)Wtsi} C57BL/6N-Nbeal2^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal megakaryocyte differentiation	J:220801
	abnormal megakaryocyte morphology	J:220801
	abnormal platelet morphology	J:220801
	abnormal platelet shape	J:220801
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased metastatic potential	J:220801
	decreased platelet alpha-granule number	J:220801
	enlarged spleen	J:220801
	increased inflammatory response	J:220801
	increased leukocyte cell number	J:211773
	increased mean platelet volume	J:211773, J:220801
	myelofibrosis	J:220801
	thrombocytopenia	J:211773, J:220801
Nbeal2^tm1Lex/Nbeal2^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	abnormal megakaryocyte morphology	J:201413
	abnormal platelet activation	J:201413
	abnormal platelet morphology	J:201413
	abnormal response to injury	J:201413
	decreased cerebral infarct size	J:201413
	decreased platelet aggregation	J:201413
	decreased platelet alpha-granule number	J:201413
	decreased susceptibility to induced thrombosis	J:201413
	enhanced megakaryocyte emperipolesis	J:201413
	enlarged spleen	J:201413
	impaired myofibroblast differentiation	J:201413
	impaired wound healing	J:201413
	increased bleeding time	J:201413
	increased megakaryocyte cell number	J:201413
	thrombocytopenia	J:201413

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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