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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ythdc2
YTH domain containing 2
MGI:2448561
21 phenotypes from 7 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ythdc2em1(IMPC)Bay/Ythdc2em1(IMPC)Bay
C57BL/6N-Ythdc2em1(IMPC)Bay/Bay 		decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased heart weight J:211773
decreased lean body mass J:211773
female infertility J:211773
increased total body fat amount J:211773
male infertility J:211773
Ythdc2em1Chhe/Ythdc2em1Chhe
involves: BALB/c * C57BL/6J 		abnormal female meiosis J:243743
arrest of male meiosis J:243743
azoospermia J:243743
decreased germ cell number J:243743
female infertility J:243743
increased male germ cell apoptosis J:243743
male infertility J:243743
small ovary J:243743
small testis J:243743
Ythdc2em1Embrp/Ythdc2em1Embrp
involves: C57BL/6J 		abnormal female meiosis J:243742
abnormal ovarian follicle morphology J:243742
absent ovarian follicles J:243742
arrest of male meiosis J:243742
azoospermia J:243742
decreased oocyte number J:243742
female infertility J:243742
increased male germ cell apoptosis J:243742
male infertility J:243742
ovary atrophy J:243742
testicular atrophy J:243742
Ythdc2em1Sky/Ythdc2em1Sky
involves: C57BL/6J * CBA 		arrest of male meiosis J:256276
decreased testis weight J:256276
female infertility J:256276
male infertility J:256276
small ovary J:256276
Ythdc2em1Sky/Ythdc2ketu
involves: C57BL/6J * CBA * FVB/NJ 		decreased testis weight J:256276
male infertility J:256276
Ythdc2em2Chhe/Ythdc2em2Chhe
involves: BALB/c * C57BL/6J 		azoospermia J:243743
decreased germ cell number J:243743
female infertility J:243743
male infertility J:243743
small ovary J:243743
small testis J:243743
Ythdc2em2Embrp/Ythdc2em2Embrp
involves: C57BL/6J 		abnormal female meiosis J:243742
abnormal ovarian follicle morphology J:243742
absent ovarian follicles J:243742
arrest of male meiosis J:243742
azoospermia J:243742
decreased oocyte number J:243742
female infertility J:243742
increased male germ cell apoptosis J:243742
male infertility J:243742
ovary atrophy J:243742
testicular atrophy J:243742
Ythdc2ketu/Ythdc2ketu
involves: C57BL/6J * FVB/NJ 		arrest of male meiosis J:256276
azoospermia J:256276
decreased testis weight J:256276
female infertility J:256276
increased male germ cell apoptosis J:256276
male infertility J:256276
small ovary J:256276
small seminiferous tubules J:256276
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory