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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gars1
glycyl-tRNA synthetase 1
MGI:2449057
14 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gars1C201R/Gars1+
Tg(CAG-GARS)DRwb/0
involves: BALB/cAnN * C3H/HeH * C57BL/6J * FVB/N 		decreased grip strength J:179811
decreased nerve conduction velocity J:179811
Gars1C201R/Gars1+
Nrcamm1J/Nrcamm1J
involves: BALB/cAnN * C3H/HeH * C57BL/6J 		abnormal axon morphology J:240096
abnormal innervation pattern to muscle J:240096
abnormal neuromuscular synapse morphology J:240096
decreased nerve conduction velocity J:240096
impaired coordination J:240096
muscle hypoplasia J:240096
tremors J:240096
Gars1C201R/Gars1+
Scn8am10J/Scn8a+
involves: BALB/cAnN * C3H/HeJ * FVB/NJ 		abnormal motor neuron innervation pattern J:240096
abnormal neuromuscular synapse morphology J:240096
decreased nerve conduction velocity J:240096
Gars1C201R/Gars1C201R
Tg(CAG-GARS)DRwb/0
involves: BALB/cAnN * C3H/HeH * C57BL/6J * FVB/N 		abnormal axon morphology J:179811
abnormal neuromuscular synapse morphology J:179811
decreased body weight J:179811
decreased nerve conduction velocity J:179811
normal mortality/aging J:179811
postnatal lethality, complete penetrance J:179811
Gars1C201R/Gars1Gt(XM256)6Byg
Tg(CAG-GARS)DRwb/0
involves: 129P2/OlaHsd * BALB/cAnN * C3H/HeH * C57BL/6J * FVB/N 		abnormal neuromuscular synapse morphology J:179811
decreased body weight J:179811
decreased nerve conduction velocity J:179811
normal mortality/aging J:179811
normal nervous system phenotype J:179811
Gars1C201R/Gars1Nmf249
Tg(CAG-GARS)DRwb/0
involves: BALB/cAnN * C3H/HeH * C57BL/6J * FVB/N 		abnormal axon morphology J:179811
abnormal neuromuscular synapse morphology J:179811
decreased body weight J:179811
normal mortality/aging J:179811
Gars1Nmf249/Gars1+
Tg(CAG-GARS)DRwb/0
involves: C57BL/6J * CAST/Ei * FVB/N 		abnormal axon morphology J:179811
abnormal neuromuscular synapse morphology J:179811
decreased body weight J:179811
decreased nerve conduction velocity J:179811
Gars1Nmf249/Gars1+
Scn8am10J/Scn8a+
involves: C57BL/6J * FVB/NJ 		abnormal neuromuscular synapse morphology J:240096
decreased nerve conduction velocity J:240096
skeletal muscle atrophy J:240096
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory