Syne2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Syne2
spectrin repeat containing, nuclear envelope 2
MGI:2449316

30 phenotypes from 7 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Syne2^cpfl8-2J/Syne2^cpfl8-2J B6;129-Syne2^cpfl8-2J/Boc	abnormal cone electrophysiology	J:278495
	abnormal ocular fundus morphology	J:278495
	abnormal retina blood vessel morphology	J:278495
	abnormal retina photoreceptor layer morphology	J:278495
	decreased total retina thickness	J:278495
	thin retina outer nuclear layer	J:278495
Syne2^cpfl8-3J/Syne2^cpfl8-3J B6.Cg-Syne2^cpfl8-3J/Boc	abnormal cone electrophysiology	J:278495
	abnormal ocular fundus morphology	J:278495
	abnormal retina blood vessel morphology	J:278495
	abnormal retina photoreceptor layer morphology	J:278495
	decreased total retina thickness	J:278495
	thin retina outer nuclear layer	J:278495
Syne2^cpfl8/Syne2^cpfl8 B6.Cg-Syne2^cpfl8/Boc	abnormal cell nucleus morphology	J:229433
	abnormal cone electrophysiology	J:229433
	abnormal Muller cell morphology	J:229433
	abnormal retina bipolar cell morphology	J:229433
	abnormal retina horizontal cell morphology	J:229433
	abnormal retina outer plexiform layer morphology	J:229433
	abnormal rod electrophysiology	J:229433
	abnormal synapse morphology	J:229433
	decreased retina cone cell number	J:229433
	increased retina apoptosis	J:229433
	short photoreceptor inner segment	J:229433
	short photoreceptor outer segment	J:229433
	thin retina inner nuclear layer	J:229433
	thin retina outer nuclear layer	J:229433
	thin retina outer plexiform layer	J:229433
	normal vision/eye phenotype	J:229433
Syne2^em1(IMPC)J/Syne2^em1(IMPC)J C57BL/6N-Syne2^em1(IMPC)J/J	abnormal locomotor behavior	J:211773
	decreased mean corpuscular volume	J:211773
	decreased total body fat amount	J:211773
	increased grip strength	J:211773
	increased lean body mass	J:211773
Syne2^tm1Ngl/Syne2^tm1Ngl involves: 129 * C57BL/6J	abnormal cell nucleus morphology	J:139778
	abnormal keratinocyte morphology	J:139778
	decreased fibroblast cell migration	J:139778
	thick epidermis	J:139778
Syne2^tm1Rexu/Syne2^tm1Rexu involves: 129 * C57BL/6	normal muscle phenotype	J:118671
Tg(Ckm-Syne2)1Rexu/0 involves: FVB	abnormal neuromuscular synapse morphology	J:118671

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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