Scarf1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Scarf1
scavenger receptor class F, member 1
MGI:2449455

29 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Scarf1^tm1Ishi/Scarf1^tm1Ishi involves: 129S7/SvEvBrd * C57BL/6J	no abnormal phenotype detected	J:91911
Scarf1^tm1Tkms/Scarf1^tm1Tkms involves: C57BL/6	abnormal B cell physiology	J:208237
	abnormal cell physiology	J:208237
	abnormal dendritic cell physiology	J:208237
	abnormal spleen morphology	J:208237
	alopecia	J:208237
	normal cellular phenotype	J:208237
	enlarged spleen	J:208237
	glomerulonephritis	J:208237
	hematuria	J:208237
	normal immune system phenotype	J:208237
	impaired macrophage phagocytosis	J:208237
	increased anti-histone antibody level	J:208237
	increased anti-nuclear antigen antibody level	J:208237
	increased anti-single stranded DNA antibody level	J:208237
	increased B cell number	J:208237
	increased blood urea nitrogen level	J:208237
	increased CD4-positive, alpha-beta T cell number	J:208237
	increased IgG level	J:208237
	increased lymphocyte cell number	J:208237
	increased spleen germinal center size	J:208237
	increased susceptibility to systemic lupus erythematosus	J:208237
	increased T follicular helper cell number	J:208237
	increased urine protein level	J:208237
	loss of vibrissae	J:208237
	normal mortality/aging	J:208237
	pyuria	J:208237
	renal glomerular immunoglobulin deposits	J:208237
	skin inflammation	J:208237

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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