Il36g Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il36g
interleukin 36G
MGI:2449929

23 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il36g^tm1Lex/Il36g^tm1Lex involves: 129S5/SvEvBrd	decreased CD4-positive, alpha-beta T cell number	J:256437
	decreased interleukin-9 secretion	J:256437
	decreased susceptibility to induced colitis	J:256437
	hindlimb paralysis	J:280917
	impaired neutrophil recruitment	J:280917
	increased CD4-positive, alpha-beta T cell number	J:256437
	increased regulatory T cell number	J:256437
	increased susceptibility to Herpesvirales infection	J:280917
	increased susceptibility to Herpesvirales infection induced morbidity/mortality	J:280917
Il36g^tm1Lex/Il36g^tm1Lex involves: 129S5/SvEvBrd * C57BL/6	abnormal cytokine level	J:296074
	abnormal macrophage activation involved in immune response	J:296074
	impaired macrophage phagocytosis	J:296074
	increased susceptibility to bacterial infection	J:296074
	increased susceptibility to bacterial infection induced morbidity/mortality	J:296074
Il36g^tm1Lex/Il36g^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	abnormal interleukin level	J:264077
	abnormal macrophage morphology	J:264077
	abnormal tumor necrosis factor level	J:264077
	decreased alveolar macrophage number	J:264077
	increased CD11b-high dendritic cell number	J:264077
	increased macrophage apoptosis	J:264077
	increased susceptibility to Orthomyxoviridae infection	J:264077
	increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality	J:264077
	increased susceptibility to weight loss	J:264077

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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