Tph2 Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tph2
tryptophan hydroxylase 2
MGI:2651811

11 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Agrp^{tm2(HBEGF)Rpa}/Agrp⁺ Tph2^tm1Mscl/Tph2^tm1Mscl involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * C57BL/6NCr	abnormal eating behavior	J:182577
	abnormal postnatal growth/weight/body size	J:182577
	decreased serotonin level	J:182577
Gsk3b^tm1Jrw/Gsk3b⁺ Tph2^tm1Mca/Tph2^tm1Mca involves: 129 * 129S6/SvEvTac * C57BL/6J	abnormal social investigation	J:131619
	normal behavior/neurological phenotype	J:131619
Tph1^tm2Lex/Tph1^tm2Lex Tph2^tm1Lex/Tph2^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	abnormal emotion/affect behavior	J:144582
	abnormal response to novel object	J:144582
	decreased body length	J:144582
	decreased body weight	J:144582
	decreased percent body fat/body weight	J:144582
	decreased serotonin level	J:144582
	decreased thermal nociceptive threshold	J:144582

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24