Plekhg5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plekhg5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
MGI:2652860

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plekhg5^tm1.1Jbar/Plekhg5^tm1.1Jbar involves: 129S1/Sv * 129X1/SvJ	abnormal angiogenesis	J:155152
	abnormal artery development	J:155152
	abnormal coronary vessel morphology	J:155152
	abnormal kidney vasculature morphology	J:155152
	decreased angiogenesis	J:155152
Plekhg5^tm1Jbar/Plekhg5^tm1Jbar Tg(Tek-cre)1Ywa/0 involves: C57BL/6 * SJL	abnormal blood vessel morphology	J:195233
	abnormal heart left ventricle morphology	J:195233
	abnormal vascular endothelial cell morphology	J:195233
	decreased heart ventricle muscle contractility	J:195233
	edema	J:195233
	impaired skin barrier function	J:195233
	increased vascular permeability	J:195233

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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