Dmrta2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dmrta2
doublesex and mab-3 related transcription factor like family A2
MGI:2653629

26 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dmrta2^tm1.1Fuma/Dmrta2^tm1.1Fuma Tg(Nes-cre)1Kag/0 involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * SJL	normal nervous system phenotype	J:203109
	telencephalon hypoplasia	J:203109
Dmrta2^tm1.2Fuma/Dmrta2^tm1.2Fuma involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * FVB/N * SJL	abnormal cerebral cortex morphology	J:203109
	abnormal neuronal precursor proliferation	J:203109
	absent hippocampus	J:203109
	decreased neuron number	J:203109
	decreased neuronal precursor cell number	J:203109
	normal nervous system phenotype	J:203109
	small olfactory bulb	J:203109
	telencephalon hypoplasia	J:203109
Dmrta2^tm1Ejbd/Dmrta2^tm1Ejbd involves: C57BL/6	abnormal brain commissure morphology	J:215514
	abnormal cerebral cortex morphology	J:215514
	abnormal cerebral hemisphere morphology	J:215514
	abnormal cortical ventricular zone morphology	J:215514
	abnormal hippocampus morphology	J:215514
	abnormal neocortex morphology	J:215514
	abnormal nervous system tract morphology	J:215514
	abnormal neuronal precursor proliferation	J:215514
	abnormal subplate morphology	J:215514
	abnormal telencephalon morphology	J:215514
	absent choroid plexus	J:215514
	absent dentate gyrus	J:215514
	absent gastric milk in neonates	J:215514
	absent hippocampus	J:215514
	decreased body size	J:215514
	decreased Cajal-Retzius cell number	J:215514
	limb grasping	J:215514
	neonatal lethality, incomplete penetrance	J:215514
	normal nervous system phenotype	J:215514
	postnatal growth retardation	J:215514
	small olfactory bulb	J:215514
	thickened cerebral cortex	J:215514
	thin cerebral cortex	J:215514

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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