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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dmrta2
doublesex and mab-3 related transcription factor like family A2
MGI:2653629
26 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dmrta2tm1.1Fuma/Dmrta2tm1.1Fuma
Tg(Nes-cre)1Kag/0
involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * SJL 		normal nervous system phenotype J:203109
telencephalon hypoplasia J:203109
Dmrta2tm1.2Fuma/Dmrta2tm1.2Fuma
involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * FVB/N * SJL 		abnormal cerebral cortex morphology J:203109
abnormal neuronal precursor proliferation J:203109
absent hippocampus J:203109
decreased neuron number J:203109
decreased neuronal precursor cell number J:203109
normal nervous system phenotype J:203109
small olfactory bulb J:203109
telencephalon hypoplasia J:203109
Dmrta2tm1Ejbd/Dmrta2tm1Ejbd
involves: C57BL/6 		abnormal brain commissure morphology J:215514
abnormal cerebral cortex morphology J:215514
abnormal cerebral hemisphere morphology J:215514
abnormal cortical ventricular zone morphology J:215514
abnormal hippocampus morphology J:215514
abnormal neocortex morphology J:215514
abnormal nervous system tract morphology J:215514
abnormal neuronal precursor proliferation J:215514
abnormal subplate morphology J:215514
abnormal telencephalon morphology J:215514
absent choroid plexus J:215514
absent dentate gyrus J:215514
absent gastric milk in neonates J:215514
absent hippocampus J:215514
decreased body size J:215514
decreased Cajal-Retzius cell number J:215514
limb grasping J:215514
neonatal lethality, incomplete penetrance J:215514
normal nervous system phenotype J:215514
postnatal growth retardation J:215514
small olfactory bulb J:215514
thickened cerebral cortex J:215514
thin cerebral cortex J:215514
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory