Otud7b Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Otud7b
OTU domain containing 7B
MGI:2654703

13 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Otud7b^{tm1(NCOM)Cmhd}/Otud7b^{tm1(NCOM)Cmhd} C57BL/6N-Otud7b^{tm1(NCOM)Cmhd}/Tcp	decreased body weight	J:165965
	decreased circulating cholesterol level	J:165965
Otud7b^{tm1(NCOM)Cmhd}/Otud7b^{tm1(NCOM)Cmhd} involves: C57BL/6N	abnormal granulocyte physiology	J:209709
Otud7b^{tm1b(EUCOMM)Wtsi}/Otud7b^{tm1b(EUCOMM)Wtsi} C57BL/6N-Otud7b^{tm1b(EUCOMM)Wtsi}/Wtsi	fusion of vertebral arches	J:239583
	muscular ventricular septal defect	J:239583
	preweaning lethality, complete penetrance	J:211773
Otud7b^tm1Dgen/Otud7b^tm1Dgen involves: 129 * C57BL/6	decreased activation-induced B cell apoptosis	J:194553
	decreased body weight	J:194553
	decreased susceptibility to bacterial infection	J:194553
	decreased susceptibility to bacterial infection induced morbidity/mortality	J:194553
	increased B cell number	J:194553
	increased B cell proliferation	J:194553
	increased IgA level	J:194553
	lymphoid hyperplasia	J:194553

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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