Ostm1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ostm1
osteopetrosis associated transmembrane protein 1
MGI:2655574

41 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ostm1^gl/Ostm1^gl GL/Le Edar^dl-J +/+ Ostm1^gl/J	abnormal coat/hair pigmentation	J:15551
	abnormal dentin mineralization	J:13053
	abnormal gait	J:13053
	abnormal hair shaft melanin granule distribution	J:217031
	abnormal incisor morphology	J:13053
	abnormal mental foramen morphology	J:13053
	abnormal molar crown morphology	J:13053
	abnormal molar root morphology	J:13053
	abnormal skeleton development	J:5561
	cachexia	J:13053
	delayed eyelid opening	J:13053
	eye inflammation	J:13053
	failure of bone ossification	J:13053
	failure of bone resorption	J:5561, J:13053
	failure of tooth eruption	J:13053
	normal homeostasis/metabolism phenotype	J:29151
	osteopetrosis	J:82658
	premature death	J:13053
	short lower incisors	J:5561
	short snout	J:13053
Ostm1^gl/Ostm1^om involves: C3HeB/FeJ	abnormal coat/hair pigmentation	J:195249
	absent incisors	J:195249
	premature death	J:195249
Ostm1^om/Ostm1^om C3HeB/FeJ-Ostm1^om	abnormal coat/hair pigmentation	J:195249
	abnormal compact bone morphology	J:195249
	abnormal deltoid tuberosity morphology	J:195249
	abnormal femur morphology	J:195249
	abnormal incisor morphology	J:195249
	abnormal long bone morphology	J:195249
	abnormal maxilla morphology	J:195249
	abnormal maxillary zygomatic process morphology	J:195249
	abnormal molar morphology	J:195249
	abnormal rib morphology	J:195249
	abnormal trabecular bone morphology	J:195249
	decreased body size	J:195249
	decreased bone mineral density	J:195249
	decreased circulating LDL cholesterol level	J:195249
	decreased circulating triglyceride level	J:195249
	decreased hemoglobin content	J:195249
	decreased lean body mass	J:195249
	decreased total body fat amount	J:195249
	failure of tooth eruption	J:195249
	increased circulating alkaline phosphatase level	J:195249
	lethality at weaning, incomplete penetrance	J:195249
	osteopetrosis	J:195249
	premature death	J:195249
	short femur	J:195249
	short incisors	J:195249

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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