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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Btla
B and T lymphocyte associated
MGI:2658978
13 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Btlatm1Dgra/Btlatm1Dgra
involves: C57BL/6 		abnormal peripheral T cell anergy J:147751
abnormal T cell activation J:147751
Btlatm1Kay/Btlatm1Kay
involves: 129S6/SvEvTac * C57BL/6J 		abnormal T cell activation J:89864
Btlatm1Kmm/Btlatm1Kmm
B6.129S-Btlatm1Kmm 		abnormal T cell activation J:119356
decreased interferon-gamma secretion J:119356
decreased interleukin-2 secretion J:119356
decreased T cell proliferation J:119356
increased length of allograft survival J:119356
increased T cell proliferation J:119356
Btlatm1Kmm/Btlatm1Kmm
involves: 129S/SvEv 		abnormal humoral immune response J:84084
increased B cell proliferation J:84084
increased IgG1 level J:84084
increased IgG2a level J:84084
increased IgG2b level J:84084
increased susceptibility to experimental autoimmune encephalomyelitis J:84084
increased T cell proliferation J:84084
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory