Synm Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Synm
synemin, intermediate filament protein
MGI:2661187

47 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Synm^{tm1.1(KOMP)Vlcg}/Synm^{tm1.1(KOMP)Vlcg} C57BL/6N-Synm^{tm1.1(KOMP)Vlcg}/Ucd	abnormal vocalization	J:211773
Synm^{tm1.1(KOMP)Vlcg}/Synm^{tm1.1(KOMP)Vlcg} involves: C57BL/6NTac	abnormal heart echocardiography feature	J:257039
	abnormal heart morphology	J:257039
	abnormal muscle fiber morphology	J:224030
	abnormal muscle morphology	J:224030
	abnormal muscle physiology	J:224030
	abnormal myocardial fiber physiology	J:257039
	abnormal sarcolemma morphology	J:224030
	abnormal skeletal muscle morphology	J:224030
	cardiac fibrosis	J:257039
	cardiac hypertrophy	J:257039
	cardiomyopathy	J:257039
	decreased cardiac output	J:257039
	decreased cardiac stroke volume	J:257039
	decreased heart left ventricle muscle contractility	J:257039
	decreased heart left ventricle posterior wall thickness	J:257039
	decreased skeletal muscle mass	J:224030
	decreased skeletal muscle size	J:224030
	dilated heart left ventricle	J:257039
	heart left ventricle hypertrophy	J:257039
	increased body weight	J:257039
	increased heart rate	J:257039
	increased heart weight	J:257039
	increased muscle fatigability	J:224030
	increased myocardial fiber size	J:257039
	muscle twitch	J:224030
	myocardium hypertrophy	J:257039
	skeletal muscle necrosis	J:224030
Synm^tm1.1Ics/Synm^tm1.1Ics involves: 129S2/SvPas * C57BL/6 * FVB/N * SJL	abnormal muscle electrophysiology	J:268425
	abnormal sarcolemma morphology	J:268425
	abnormal sarcomere morphology	J:268425
	abnormal skeletal muscle fiber morphology	J:268425
	abnormal skeletal muscle fiber type ratio	J:268425
	abnormal skeletal muscle regeneration	J:268425
	centrally nucleated skeletal muscle fibers	J:268425
	hyperactivity	J:268425
	increased basal metabolism	J:268425
	increased body length	J:268425
	increased fluid intake	J:268425
	increased lean body mass	J:268425
	increased oxygen consumption	J:268425
	increased satellite cell number	J:268425
	increased skeletal muscle fiber diameter	J:268425
	increased skeletal muscle mass	J:268425
	increased susceptibility to injury	J:268425
	long tibia	J:268425
	myopathy	J:268425
	skeletal muscle fiber degeneration	J:268425

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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