Mogat2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mogat2
monoacylglycerol O-acyltransferase 2
MGI:2663253

24 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mogat2^em1(IMPC)Mbp/Mogat2^em1(IMPC)Mbp C57BL/6N-Mogat2^em1(IMPC)Mbp/MbpMmucd	abnormal seminal vesicle morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	decreased locomotor activity	J:211773
	decreased prepulse inhibition	J:211773
	enlarged spleen	J:211773
	small seminal vesicle	J:211773
	small testis	J:211773
Mogat2^tm1.1Ryyo/Mogat2^tm1.1Ryyo B6.Cg-Mogat2^tm1.1Ryyo	decreased circulating triglyceride level	J:155626
Mogat2^tm1.1Ryyo/Mogat2^tm1.1Ryyo B6.Cg-Mogat2^tm1.1Ryyo	normal digestive/alimentary phenotype	J:155626
Mogat2^tm1Far/Mogat2⁺ B6.129S4-Mogat2^tm1Far	decreased susceptibility to diet-induced obesity	J:149373
Mogat2^tm1Far/Mogat2^tm1Far B6.129S4-Mogat2^tm1Far	abnormal intestinal lipid absorption	J:149373
	decreased brown fat cell number	J:149373
	decreased circulating cholesterol level	J:149373
	decreased circulating insulin level	J:149373
	decreased circulating LDL cholesterol level	J:149373
	decreased circulating triglyceride level	J:149373
	decreased circulating VLDL cholesterol level	J:149373
	decreased percent body fat/body weight	J:149373
	decreased susceptibility to diet-induced obesity	J:149373
	decreased susceptibility to hepatic steatosis	J:149373
	decreased susceptibility to hyperlipidemia	J:149373
	improved glucose tolerance	J:149373
	increased body temperature	J:149373
	increased oxygen consumption	J:149373

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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