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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Kiss1
KiSS-1 metastasis-suppressor
MGI:2663985
48 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Kiss1tm1.1(cre/EGFP)Stei/Kiss1+
involves: 129S6/SvEvTac * C57BL/6NCr 		normal nervous system phenotype J:178519
Kiss1tm1Coll/Kiss1tm1Coll
involves: 129S/SvEv * 129S6/SvEvTac 		abnormal adrenal gland morphology J:122381
abnormal circulating estradiol level J:122381
abnormal female reproductive system morphology J:122381
abnormal gametogenesis J:122381
abnormal gland morphology J:122381
abnormal male preputial gland morphology J:122381
abnormal male reproductive system morphology J:122381
abnormal seminal vesicle development J:122381
abnormal Sertoli cell development J:122381
abnormal sex gland morphology J:122381
abnormal spermatogenesis J:122381
abnormal spermiogenesis J:122381
abnormal uterus development J:122381
abnormal vagina orifice morphology J:122381
absent corpus luteum J:122381
absent estrous cycle J:122381
absent mature ovarian follicles J:122381
absent sexual maturation J:122381
anovulation J:122381
azoospermia J:122381
decreased body weight J:122381
decreased circulating estradiol level J:122381
decreased circulating follicle stimulating hormone level J:122381
decreased circulating luteinizing hormone level J:122381
decreased circulating testosterone level J:122381
decreased kidney weight J:122381
decreased liver weight J:122381
decreased testis weight J:122381
decreased uterus weight J:122381
increased atretic ovarian follicle number J:122381
retention of the adrenal gland x-zone J:122381
small ovary J:122381
small penis J:122381
small salivary gland J:122381
small uterus J:122381
Kiss1tm1Rla/Kiss1tm1Rla
involves: 129S1/SvImJ 		abnormal anogenital distance J:126704
abnormal female reproductive system morphology J:126704
abnormal male reproductive system morphology J:126704
abnormal spermatid morphology J:126704
abnormal vagina epithelium morphology J:126704
absent corpus luteum J:126704
absent estrous cycle J:126704
absent ovarian follicles J:126704
decreased circulating follicle stimulating hormone level J:126704
decreased Leydig cell number J:126704
decreased ovary weight J:126704
decreased testis weight J:126704
delayed vaginal opening J:126704
female infertility J:126704
male infertility J:126704
ovary cyst J:126704
seminal vesicle hypoplasia J:126704
small male preputial gland J:126704
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory