Trpm6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trpm6
transient receptor potential cation channel, subfamily M, member 6
MGI:2675603

20 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Trpm6^tm1.1Rws/Trpm6⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	decreased circulating magnesium level	J:153718
	premature death	J:153718
Trpm6^tm1.1Rws/Trpm6^tm1.1Rws involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N	abnormal brain development	J:153718
	abnormal craniofacial development	J:153718
	abnormal facial morphology	J:153718
	abnormal neural tube closure	J:153718
	abnormal reproductive system physiology	J:153718
	decreased fetal size	J:153718
	decreased fetal weight	J:153718
	embryonic lethality during organogenesis, incomplete penetrance	J:153718
	exencephaly	J:153718
	lethality throughout fetal growth and development, incomplete penetrance	J:153718
	postnatal lethality, incomplete penetrance	J:153718
	premature death	J:153718
	short snout	J:153718
	spina bifida occulta	J:153718
Trpm6^{tm1b(KOMP)Wtsi}/Trpm6⁺ C57BL/6N-Trpm6^{tm1b(KOMP)Wtsi}/Orl	abnormal eye anterior chamber depth	J:211773
	decreased circulating phosphate level	J:211773
	decreased mean corpuscular volume	J:211773
	increased body length	J:211773
	increased grip strength	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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