Foxo6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Foxo6
forkhead box O6
MGI:2676586

26 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Foxo6^{tm1(KOMP)Vlcg}/Foxo6^{tm1(KOMP)Vlcg} B6J.B6NTac-Foxo6^{tm1(KOMP)Vlcg}	abnormal enzyme/coenzyme activity	J:236585
	abnormal gluconeogenesis	J:236585
	abnormal Kupffer cell morphology	J:236585
	decreased circulating cholesterol level	J:236585
	decreased circulating glucose level	J:236585
	decreased circulating insulin level	J:236585
	decreased fasting circulating glucose level	J:236585
	decreased food intake	J:236585
	decreased liver triglyceride level	J:236585
	decreased respiratory quotient	J:236585
	decreased susceptibility to diet-induced hepatic steatosis	J:236585
	decreased susceptibility to weight gain	J:236585
	decreased white fat cell size	J:236585
	impaired macrophage chemotaxis	J:236585
	improved glucose tolerance	J:236585
	increased insulin sensitivity	J:236585
	increased oxygen consumption	J:236585
Foxo6^tm1Abru/Foxo6^tm1Abru involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal brain wave pattern	J:191193
	abnormal temporal memory	J:191193
	normal behavior/neurological phenotype	J:191193
	decreased dendritic spine density	J:191193
	decreased dendritic spine number	J:191193
	decreased locomotor activity	J:191193
	impaired long-term object recognition memory	J:191193
	increased dendritic spine length	J:191193
	increased grooming behavior	J:191193

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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