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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nlrp12
NLR family, pyrin domain containing 12
MGI:2676630
11 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Nlrp12tm1Jpyt/Nlrp12tm1Jpyt
B6.Cg-Nlrp12tm1Jpyt 		abnormal leukocyte migration J:164725
decreased neutrophil cell number J:164725
decreased susceptibility to type IV hypersensitivity reaction J:164725
impaired neutrophil chemotaxis J:164725
Nlrp12tm1Jpyt/Nlrp12tm1Jpyt
Not Specified 		normal immune system phenotype J:173245
Nlrp12tm1Tdk/Nlrp12tm1Tdk
B6.Cg-Nlrp12tm1Tdk 		abnormal chemokine level J:178951
abnormal cytokine level J:178951
enlarged spleen J:178951
increased incidence of tumors by chemical induction J:178951
increased inflammatory response J:178951
increased susceptibility to induced colitis J:178951
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory