Il17f Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il17f
interleukin 17F
MGI:2676631

16 phenotypes from 6 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il17a/Il17f^tm1.1Impr/Il17a/Il17f^tm1.1Impr involves: C57BL/6	abnormal effector T cell morphology	J:187400
	absent gamma-delta T cells	J:187400
	decreased interleukin-17 secretion	J:187400
	normal immune system phenotype	J:187400, J:189794
	increased gamma-delta T cell number	J:187400
	increased T cell proliferation	J:187400
Il17f^{tm1(Thy1)Weav}/Il17f^{tm1(Thy1)Weav} involves: C57BL/6	no abnormal phenotype detected	J:143729
Il17f^tm1Awai/Il17f⁺ involves: 129S6/SvEvTac * C57BL/6	decreased interleukin-17 secretion	J:144710
Il17f^tm1Awai/Il17f^tm1Awai involves: 129S6/SvEvTac * C57BL/6	abnormal immune system physiology	J:144710
	decreased interleukin-17 secretion	J:144710
Il17f^tm1Cdon/Il17f^tm1Cdon involves: C57BL/6	chronic inflammation	J:136279
	decreased acute inflammation	J:136279
	decreased interleukin-17 secretion	J:136279
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:136279
	decreased susceptibility to induced colitis	J:136279
	increased IgG2a level	J:136279
Il17f^tm1Yiw/Il17f^tm1Yiw involves: 129P2/OlaHsd * C57BL/6	increased susceptibility to bacterial infection	J:143719
Tg(Scgb1a1-Il17f,GFP)1Cdon/? C57BL/6-Tg(Scgb1a1-Il17f,GFP)1Cdon	abnormal respiratory mucosa morphology	J:136279
	lung inflammation	J:136279

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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