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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mir122
microRNA 122
MGI:2676805
31 phenotypes from 3 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Mir122tm1.1Apts/Mir122tm1.1Apts
involves: 129 * C57BL/6 		abnormal Ito cell morphology J:190066
abnormal liver morphology J:190066
decreased circulating cholesterol level J:190066
decreased circulating HDL cholesterol level J:190066
decreased circulating triglyceride level J:190066
decreased circulating VLDL cholesterol level J:190066
decreased liver glycogen level J:190066
hepatic steatosis J:190066
increased circulating alanine transaminase level J:190066
increased circulating alkaline phosphatase level J:190066
increased circulating interleukin-6 level J:190066
increased hepatocellular carcinoma incidence J:190066
increased liver cholesterol level J:190066
increased liver triglyceride level J:190066
increased macrophage cell number J:190066
increased monocyte cell number J:190066
liver fibrosis J:190066
liver inflammation J:190066
Mir122tm1.1Kgh/Mir122+
involves: 129S1/Sv * 129X1/SvJ 		increased hepatocellular carcinoma incidence J:190067
Mir122tm1.1Kgh/Mir122tm1.1Kgh
involves: 129S1/Sv * 129X1/SvJ 		abnormal circulating enzyme level J:190067
decreased circulating cholesterol level J:190067
decreased circulating HDL cholesterol level J:190067
hepatic steatosis J:190067
increased bile salt level J:190067
increased circulating alanine transaminase level J:190067
increased circulating alkaline phosphatase level J:190067
increased circulating interleukin-6 level J:190067
increased hepatocellular carcinoma incidence J:190067
increased liver triglyceride level J:190067
increased tumor growth/size J:190067
liver fibrosis J:190067
liver inflammation J:190067
Mir122tm1.2Kgh/Mir122+
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA 		increased hepatocellular carcinoma incidence J:190067
Mir122tm1.2Kgh/Mir122tm1.2Kgh
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA 		abnormal circulating enzyme level J:190067
abnormal lipid homeostasis J:190067
abnormal liver physiology J:190067
abnormal oval cell physiology J:190067
bile duct proliferation J:190067
decreased circulating cholesterol level J:190067
decreased circulating HDL cholesterol level J:190067
decreased circulating LDL cholesterol level J:190067
decreased liver glycogen level J:190067
increased bile salt level J:190067
increased circulating alanine transaminase level J:190067
increased circulating alkaline phosphatase level J:190067
increased circulating interleukin-6 level J:190067
increased hepatocellular carcinoma incidence J:190067
increased interleukin-6 secretion J:190067
increased liver triglyceride level J:190067
increased liver tumor incidence J:190067
increased monocyte cell number J:190067
increased neutrophil cell number J:190067
increased tumor necrosis factor secretion J:190067
liver fibrosis J:190067
liver inflammation J:190067
microvesicular hepatic steatosis J:190067
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory