Mir140 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mir140
microRNA 140
MGI:2676825

31 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mir140^em1Asah/Mir140^em1Asah involves: C57BL/6J * DBA	decreased cranium height	J:278573
Mir140^em1Tkob/Mir140⁺ C57BL/6-Mir140^em1Tkob	abnormal cartilage development	J:286036
	abnormal epiphyseal plate morphology	J:286036
	abnormal long bone epiphyseal plate morphology	J:286036
	delayed bone ossification	J:286036
	platyspondylia	J:286036
Mir140^em1Tkob/Mir140^em1Tkob C57BL/6-Mir140^em1Tkob	abnormal cartilage development	J:286036
	abnormal epiphyseal plate morphology	J:286036
	abnormal long bone epiphyseal plate morphology	J:286036
	decreased body size	J:286036
	decreased bone mineralization	J:286036
	delayed bone ossification	J:286036
	platyspondylia	J:286036
	short nasal bone	J:286036
	short snout	J:286036
	small vertebral body	J:286036
Mir140^tm1.1Asah/Mir140^tm1.1Asah involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	abnormal chondrocyte physiology	J:160358
	abnormal skeleton morphology	J:160358
	abnormal skeleton physiology	J:160358
	decreased body height	J:160358
	decreased body weight	J:160358
	decreased length of long bones	J:160358
	decreased long bone epiphyseal plate size	J:160358
	domed cranium	J:160358
	increased susceptibility to induced arthritis	J:160358
	osteoarthritis	J:160358
	postnatal growth retardation	J:160358
	short maxilla	J:160358
	short nasal bone	J:160358
	short snout	J:160358
	normal skeleton phenotype	J:160358
Mir140^tm1.1Tkob/Mir140^tm1.1Tkob involves: 129S4/SvJae * C57BL/6	decreased body size	J:286036
	short snout	J:286036
Mir140^tm1.1Tkob/Mir140^tm1.1Tkob involves: 129S4/SvJae * C57BL/6 * SJL	abnormal basicranium morphology	J:174096
	abnormal long bone epiphyseal plate morphology	J:174096
	abnormal skeleton development	J:174096
	decreased body size	J:174096
	decreased body weight	J:174096
	decreased cranium height	J:174096
	decreased length of long bones	J:174096
	decreased long bone epiphyseal plate size	J:174096
	increased width of hypertrophic chondrocyte zone	J:174096
	postnatal growth retardation	J:174096
	short femur	J:174096
	short tibia	J:174096
	small basisphenoid bone	J:174096
Tg(Col2a1-Mir140)#Asah/0 C57BL/6-Tg(Col2a1-Mir140)#Asah	decreased susceptibility to induced arthritis	J:160358

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24