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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mir26a-1
microRNA 26a-1
MGI:2676900
18 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1.1(Mir26a-1)Coh/Gt(ROSA)26Sor+
Tg(Ins2-cre)25Mgn/0
involves: C57BL/6 * DBA 		decreased circulating insulin level J:286108
decreased fasting circulating glucose level J:286108
decreased insulin secretion J:286108
decreased pancreatic beta cell mass J:286108
decreased susceptibility to diet-induced obesity J:286108
improved glucose tolerance J:286108
increased insulin sensitivity J:286108
small pancreatic islets J:286108
Mir26a-1em1Xfu/Mir26a-1em1Xfu
Mir26a-2em1Xfu/Mir26a-2em1Xfu
involves: C57BL/6 		abnormal pancreatic alpha cell morphology J:286108
decreased pancreatic islet number J:286108
enlarged pancreatic islets J:286108
increased circulating glucose level J:286108
increased circulating insulin level J:286108
increased fasting circulating glucose level J:286108
increased pancreatic beta cell proliferation J:286108
increased susceptibility to diet-induced obesity J:286108
insulin resistance J:286108
pancreatic islet hyperplasia J:286108
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory