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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Thoc6
THO complex 6
MGI:2677480
17 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Thoc6em1Schaf/Thoc6+
C57BL/6JN-Thoc6em1Schaf 		no abnormal phenotype detected J:345604
Thoc6em1Schaf/Thoc6em1Schaf
C57BL/6JN-Thoc6em1Schaf 		abnormal telencephalon development J:345604
decreased embryo size J:345604
embryonic growth retardation J:345604
embryonic lethality during organogenesis, complete penetrance J:345604
increased embryonic neuroepithelial cell proliferation J:345604
increased embryonic tissue cell apoptosis J:345604
Thoc6em5(IMPC)Tcp/Thoc6+
C57BL/6NCrl-Thoc6em5(IMPC)Tcp/Tcp 		abnormal lung morphology J:211773
decreased exploration in new environment J:211773
decreased locomotor activity J:211773
decreased vertical activity J:211773
enlarged lymph nodes J:211773
enlarged ovary J:211773
shortened QRS complex duration J:211773
Thoc6em5(IMPC)Tcp/Thoc6em5(IMPC)Tcp
C57BL/6NCrl-Thoc6em5(IMPC)Tcp/Tcp 		abnormal embryo size J:211773
embryonic growth retardation J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory