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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Vsig4
V-set and immunoglobulin domain containing 4
MGI:2679720
28 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Vsig4em#Tvg/Vsig4em#Tvg
BALB/cJ-Vsig4em#Tvg 		normal neoplasm J:329456
Vsig4tm1b(EUCOMM)Hmgu/Y
C57BL/6N-Vsig4tm1b(EUCOMM)Hmgu/J 		abnormal cholesterol homeostasis J:211773
decreased circulating glucose level J:211773
decreased locomotor activity J:211773
decreased mean corpuscular hemoglobin J:211773
decreased total body fat amount J:211773
increased circulating alanine transaminase level J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating aspartate transaminase level J:211773
increased circulating potassium level J:211773
increased lean body mass J:211773
increased urine microalbumin level J:211773
Vsig4tm1b(EUCOMM)Hmgu/Vsig4tm1b(EUCOMM)Hmgu
C57BL/6N-Vsig4tm1b(EUCOMM)Hmgu/J 		abnormal sleep behavior J:211773
decreased circulating glucose level J:211773
decreased total body fat amount J:211773
hyperactivity J:211773
increased blood urea nitrogen level J:211773
increased circulating sodium level J:211773
increased heart weight J:211773
increased lean body mass J:211773
increased urine microalbumin level J:211773
increased vertical activity J:211773
Vsig4tm1Gne/Vsig4tm1Gne
C57BL/6-Vsig4tm1Gne 		abnormal enterocyte proliferation J:281762
abnormal macrophage physiology J:281762
decreased susceptibility to induced colitis J:281762
increased circulating interleukin-1 beta level J:281762
increased interleukin-1 beta secretion J:281762
increased susceptibility to experimental autoimmune encephalomyelitis J:281762
increased T-helper 1 cell number J:281762
increased T-helper 17 cell number J:281762
Vsig4tm1Gne/Vsig4tm1Gne
involves: C57BL/6N 		increased susceptibility to bacterial infection J:138691
increased susceptibility to induced morbidity/mortality J:138691
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory