Polr3a Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Polr3a
polymerase (RNA) III (DNA directed) polypeptide A
MGI:2681836

10 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Polr3a^em2(IMPC)Tcp/Polr3a⁺ C57BL/6NCrl-Polr3a^em2(IMPC)Tcp/Tcp	enlarged lymph nodes	J:211773
	enlarged urinary bladder	J:211773
	increased bone mineral content	J:211773
	increased mean platelet volume	J:211773
Polr3a^em2(IMPC)Tcp/Polr3a^em2(IMPC)Tcp C57BL/6NCrl-Polr3a^em2(IMPC)Tcp/Tcp	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Polr3a^Gt(LG04)Osb/Polr3a^Gt(LG04)Osb B6;D2-Polr3a^Gt(LG04)Osb/OsbRbrc	embryonic lethality, complete penetrance	J:250577
Polr3a^Gt(LG04)Osb/Polr3a^tm1Bebr involves: C57BL/6 * C57BL/6J * DBA/2	abnormal gait	J:250577
	normal nervous system phenotype	J:250577
Polr3a^tm1.1Bebr/Polr3a^tm1.1Bebr involves: C57BL/6J	abnormal gait	J:250577
Polr3a^tm1.1Bebr/Polr3a^tm1.1Bebr involves: C57BL/6J	normal nervous system phenotype	J:250577

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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