Obscn Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Obscn
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
MGI:2681862

14 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Obscn^tm1.1Geno/Obscn^tm1.1Geno B6.129-Obscn^tm1.1Geno	abnormal myocardial fiber physiology	J:243723
	cardiac fibrosis	J:243723
	increased heart left ventricle muscle contractility	J:243723
	increased heart rate	J:243723
	increased response of heart to induced stress	J:243723
	ventricular premature beat	J:243723
	ventricular tachycardia	J:243723
Obscn^tm1Chen/Obscn^tm1Chen involves: 129 * Black Swiss * C57BL/6 * SJL	abnormal muscle physiology	J:283623
	abnormal sarcolemma morphology	J:283623
	abnormal sarcoplasmic reticulum morphology	J:283623
	increased skeletal muscle fiber diameter	J:283623
	normal muscle phenotype	J:283623
Obscn^tm1Chen/Obscn^tm1Chen involves: 129S1/Sv * 129X1/SvJ	abnormal sarcoplasmic reticulum morphology	J:153150
	centrally nucleated skeletal muscle fibers	J:153150
	normal muscle phenotype	J:153150
	myopathy	J:153150

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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