Cep135 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cep135
centrosomal protein 135
MGI:2681869

38 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cep135^em1(IMPC)J/Cep135⁺ C57BL/6NJ-Cep135^em1(IMPC)J/J	abnormal head morphology	J:211773
	abnormal lens morphology	J:211773
	cataract	J:211773
	decreased bone mineral density	J:211773
	decreased circulating serum albumin level	J:211773
	increased circulating total protein level	J:211773
Cep135^em1(IMPC)J/Cep135^em1(IMPC)J C57BL/6NJ-Cep135^em1(IMPC)J/J	abnormal craniofacial morphology	J:211773
	abnormal head shape	J:211773
	anophthalmia	J:211773
	edema	J:211773
	facial cleft	J:211773
	microphthalmia	J:211773
	polydactyly	J:211773
	preweaning lethality, complete penetrance	J:211773
Cep135^em1Mama/Cep135^em1Mama involves: C57BL/6 * C57BL/6J * CBA	normal cellular phenotype	J:310617
	decreased neocortex size	J:310617
	microcephaly	J:310617
Cep135^em1Mama/Cep135^em2Mama involves: C57BL/6 * C57BL/6J * CBA	decreased neocortex size	J:310617
	microcephaly	J:310617
Cep135^em2Mama/Cep135^em2Mama involves: C57BL/6 * C57BL/6J * CBA	abnormal cell cycle	J:310617
	abnormal cell nucleus morphology	J:310617
	abnormal centrosome morphology	J:310617
	abnormal cerebral cortex morphology	J:310617
	abnormal cortical ventricular zone morphology	J:310617
	abnormal intestinal mucosa morphology	J:310617
	abnormal intestine development	J:310617
	abnormal lung alveolus development	J:310617
	abnormal lung development	J:310617
	abnormal mitosis	J:310617
	abnormal mitotic spindle morphology	J:310617
	abnormal nervous system physiology	J:310617
	abnormal retina morphology	J:310617
	abnormal stomach mucosa morphology	J:310617
	aneuploidy	J:310617
	chromosomal instability	J:310617
	decreased brain weight	J:310617
	decreased cell proliferation	J:310617
	decreased embryo size	J:310617
	decreased neocortex size	J:310617
	increased embryonic tissue cell apoptosis	J:310617
	microcephaly	J:310617
	neonatal lethality, complete penetrance	J:310617

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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