Whrn Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Whrn
whirlin
MGI:2682003

56 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Whrn^hb/Whrn^hb involves: BALB/c * C3H/HeH * C57BL/6J	hyperactivity	J:234901
Whrn^hb/Whrn^hb involves: BALB/c * C3H/HeH * C57BL/6J	impaired hearing	J:234901
Whrn^{tm1a(EUCOMM)Wtsi}/Whrn^{tm1a(EUCOMM)Wtsi} C57BL/6N-Whrn^{tm1a(EUCOMM)Wtsi}	increased or absent threshold for auditory brainstem response	J:235390
Whrn^{tm1a(EUCOMM)Wtsi}/Whrn^{tm1a(EUCOMM)Wtsi} C57BL/6N-Whrn^{tm1a(EUCOMM)Wtsi}/Wtsi	increased thermal nociceptive threshold	J:175295
Whrn^{tm1b(EUCOMM)Wtsi}/Whrn^{tm1b(EUCOMM)Wtsi} involves: 129S7/SvEvBrd * C57BL/6N	abnormal cochlear frequency tuning	J:235390
	abnormal cochlear hair bundle transient lateral links morphology	J:235390
	abnormal cochlear outer hair cell physiology	J:235390
	abnormal distortion product otoacoustic emission	J:235390
	abnormal outer hair cell stereociliary bundle morphology	J:235390
	abnormal vestibular hair cell stereociliary bundle morphology	J:235390
	absent distortion product otoacoustic emissions	J:235390
	normal behavior/neurological phenotype	J:235390
	normal hearing/vestibular/ear phenotype	J:235390
	impaired hearing	J:235390
	increased or absent threshold for auditory brainstem response	J:235390
	short vestibular hair cell stereocilia	J:235390
Whrn^tm1Tili/Whrn^tm1Tili involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cone electrophysiology	J:160677
	abnormal outer hair cell stereociliary bundle morphology	J:160677
	abnormal retina photoreceptor morphology	J:160677
	abnormal rod electrophysiology	J:160677
	absent distortion product otoacoustic emissions	J:160677
	decreased cochlear hair cell number	J:160677
	decreased outer hair cell stereocilia number	J:160677
	impaired hearing	J:160677
	retina degeneration	J:160677
	short photoreceptor outer segment	J:160677
	thin retina outer nuclear layer	J:160677
Whrn^wi/Whrn⁺ involves: C57BL/6J * STOCK a Tyrp1^b Myo5a^d Oca2^p Ednrb^s	abnormal cochlear inner hair cell morphology	J:77939
	short inner hair cell stereocilia	J:77939
Whrn^wi/Whrn^wi involves: C57BL/6J * STOCK a Tyrp1^b Myo5a^d Oca2^p Ednrb^s	abnormal cochlear hair cell stereociliary bundle morphology	J:77939
	abnormal cochlear inner hair cell morphology	J:48657
	abnormal cochlear outer hair cell morphology	J:158897
	abnormal gait	J:269
	abnormal maternal nurturing	J:269
	abnormal outer hair cell stereociliary bundle morphology	J:48657, J:77939, J:122600, J:158897
	circling	J:269, J:5037, J:48657
	cochlear hair cell degeneration	J:48657
	cochlear inner hair cell degeneration	J:48657, J:77939
	cochlear outer hair cell degeneration	J:48657, J:77939
	deafness	J:269, J:5037, J:48657
	decreased body weight	J:269, J:5037, J:5538
	decreased circulating glucose level	J:5538
	decreased leukocyte cell number	J:5538
	decreased liver glycogen level	J:5538
	decreased outer hair cell stereocilia number	J:122600
	decreased seminal vesicle weight	J:5538
	decreased thymus weight	J:5037
	decreased total body fat amount	J:5538
	decreased uterus weight	J:5037
	enlarged adrenal glands	J:5037, J:5538
	head bobbing	J:269, J:48657
	head tossing	J:269, J:5037
	hyperactivity	J:5037
	impaired righting response	J:269
	impaired swimming	J:269
	increased circulating corticosterone level	J:5538
	increased heart weight	J:5538
	increased kidney weight	J:5037
	increased liver weight	J:5037
	increased oxygen consumption	J:5037, J:5538
	short inner hair cell stereocilia	J:48657, J:77939, J:122600
	short outer hair cell stereocilia	J:158897
Whrn^wi/Whrn^wi involves: STOCK a Tyrp1^b Myo5a^d Oca2^p Ednrb^s	abnormal auditory summating potential	J:235390
	abnormal outer hair cell stereociliary bundle morphology	J:235390
	absent cochlear microphonics	J:235390
	absent cochlear nerve compound action potential	J:235390
	circling	J:235390
	deafness	J:235390
	head bobbing	J:235390
	impaired righting response	J:235390
	increased or absent threshold for auditory brainstem response	J:235390
	short cochlear hair cell stereocilia	J:132633
	short inner hair cell stereocilia	J:235390
	short vestibular hair cell stereocilia	J:235390

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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