Atmin Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Atmin
ATM interactor
MGI:2682328

65 phenotypes from 6 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Atmin^gpg6/Atmin^gpg6 C3H.C-Atmin^gpg6	abnormal cardiac outflow tract development	J:217609
	abnormal embryonic neuroepithelium primary cilium morphology	J:217609
	abnormal primary cilium morphology	J:217609
	normal cardiovascular system phenotype	J:217609
	coloboma	J:217609
	decreased embryonic cilium length	J:217609
	normal digestive/alimentary phenotype	J:217609
	edema	J:217609
	exencephaly	J:217609
	interrupted aortic arch	J:217609
	left pulmonary isomerism	J:217609
	microphthalmia	J:217609
	small lung	J:217609
	thick upper lip	J:217609
Atmin^gpg6/Atmin^gpg6 involves: BALB/cAnN * C3H/HeH	abnormal craniofacial morphology	J:145068
	abnormal eye morphology	J:145068
	abnormal kidney epithelium morphology	J:211696
	abnormal motile primary cilium morphology	J:145068
	abnormal truncus arteriosus septation	J:145068
	absent lungs	J:145068
	edema	J:145068
	exencephaly	J:145068
	impaired branching involved in ureteric bud morphogenesis	J:211696
	interrupted aortic arch	J:145068
	left pulmonary isomerism	J:145068
	micrognathia	J:145068
	right aortic arch	J:145068
	right pulmonary isomerism	J:145068
	situs inversus	J:145068
	small kidney	J:211696
	spina bifida	J:145068
Atmin^gpg6/Atmin^m1H C3.C-Atmin^gpg6/Atmin^m1H	absent lungs	J:217609
	normal cardiovascular system phenotype	J:217609
	coloboma	J:217609
	normal digestive/alimentary phenotype	J:217609
	edema	J:217609
	exencephaly	J:217609
	left pulmonary isomerism	J:217609
	microphthalmia	J:217609
	small lung	J:217609
	thick upper lip	J:217609
Atmin^m1H/Atmin^m1H C3H.C-Atmin^m1H	absent lungs	J:217609
	normal cardiovascular system phenotype	J:217609
	coloboma	J:217609
	normal digestive/alimentary phenotype	J:217609
	edema	J:217609
	exencephaly	J:217609
	left pulmonary isomerism	J:217609
	microphthalmia	J:217609
	small lung	J:217609
	thick upper lip	J:217609
Atmin^tm1.1Axbe/Atmin^tm1.1Axbe involves: BALB/c * C57BL/6	abnormal cell physiology	J:167331
	abnormal craniofacial morphology	J:167331
	decreased cell proliferation	J:167331
	early cellular replicative senescence	J:167331
	exencephaly	J:167331
	lethality throughout fetal growth and development, complete penetrance	J:167331
Atmin^tm1.1Jhh/Atmin^tm1.1Jhh C57BL/6-Atmin^tm1.1Jhh	abnormal base-excision repair	J:167544
	abnormal heart position or orientation	J:167544
	abnormal respiratory system development	J:167544
	abnormal trachea development	J:167544
	absent lungs	J:167544
	absent trachea	J:167544
	normal cellular phenotype	J:167544
	decreased fetal weight	J:167544
	early cellular replicative senescence	J:167544
	exencephaly	J:167544
	fetal growth retardation	J:167544
	increased cellular sensitivity to hydrogen peroxide	J:167544
	increased cellular sensitivity to methylmethanesulfonate	J:167544
	lethality throughout fetal growth and development, complete penetrance	J:167544
	thymus hypoplasia	J:167544
Atmin^tm1.1Jhh/Atmin^tm1.1Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ B6.Cg-Cd79a^tm1(Cre)Reth Atmin^tm1.1Jhh	decreased B cell number	J:230105
	decreased IgG1 level	J:230105
	decreased immature B cell number	J:230105
	increased B cell apoptosis	J:230105
Atmin^tm1.1Jhh/Atmin^tm1.1Jhh Tg(Fcer2a-cre)5Mbu/0 B6.Cg-Atmin^tm1.1Jhh Tg(Fcer2a-cre)5Mbu	normal hematopoietic system phenotype	J:230105
	normal neoplasm	J:230105
Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Cd79a^tm1(cre)Reth/Cd79a⁺ involves: BALB/c * C57BL/6	abnormal B cell differentiation	J:191832
	abnormal B cell physiology	J:191832
	decreased immature B cell number	J:191832
	decreased mature B cell number	J:191832
	decreased pre-B cell number	J:191832
	decreased spleen weight	J:191832
	small spleen	J:191832
Atmin^tm1.2Jhh/Atmin^tm1.2Jhh Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * CBA	decreased B cell number	J:191832
	decreased erythrocyte cell number	J:191832
	decreased lymphocyte cell number	J:191832
	decreased mature B cell number	J:191832
	decreased pre-B cell number	J:191832
	normal immune system phenotype	J:191832
Atmin^tm1Axbe/Atmin^tm1Axbe Tg(Nes-cre)1Kln/0 involves: C57BL/6 * SJL	astrocytosis	J:167331
	decreased body weight	J:167331
	decreased neuron number	J:167331
	hyperactivity	J:167331
	increased anxiety-related response	J:167331
	loss of dopaminergic neurons	J:167331
	neurodegeneration	J:167331
	premature death	J:167331

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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