Ffar1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ffar1
free fatty acid receptor 1
MGI:2684079

25 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ffar1^{tm1.1(KOMP)Vlcg}/Ffar1^{tm1.1(KOMP)Vlcg} C57BL/6N-Ffar1^{tm1.1(KOMP)Vlcg}/Ucd	preweaning lethality, incomplete penetrance	J:211773
Ffar1^tm1Dgen/Ffar1^tm1Dgen B6.129P2-Ffar1^tm1Dgen	normal homeostasis/metabolism phenotype	J:141957
Ffar1^tm1Dgen/Ffar1^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	abnormal circulating hormone level	J:141957
	abnormal circulating insulin level	J:141957
	abnormal triglyceride level	J:141957
	decreased amylin secretion	J:141957
	decreased circulating glucagon level	J:141957
	decreased circulating triglyceride level	J:141957
	normal homeostasis/metabolism phenotype	J:141957
	increased food intake	J:141957
	increased liver triglyceride level	J:141957
Ffar1^tm1Dgen/Ffar1^tm1Dgen involves: 129P2/OlaHsd * C57BL/6N	abnormal gustatory system physiology	J:161517
	abnormal sensory neuron physiology	J:161517
	abnormal taste sensitivity	J:161517
Ffar1^tm1Heed/Ffar1^tm1Heed Not Specified	abnormal circulating triglyceride level	J:129843
	abnormal gluconeogenesis	J:129843
	decreased circulating insulin level	J:129843
	decreased insulin secretion	J:129843
	decreased susceptibility to diet-induced hepatic steatosis	J:129843
	improved glucose tolerance	J:129843
	increased insulin sensitivity	J:129843
Ffar1^tm1Lex/Ffar1^tm1Lex involves: 129 * C57BL/6	decreased insulin secretion	J:122092
Ffar1^tm1Lex/Ffar1^tm1Lex involves: C57BL/6 * C57BL/6J	abnormal glucagon secretion	J:200805
Ffar1^tm1Lex/Ffar1^tm1Lex involves: C57BL/6 * C57BL/6J	increased circulating glucose level	J:200805
Tg(Pdx1-Ffar1)AHeed/0 Not Specified	abnormal pancreatic beta cell physiology	J:129843
	decreased insulin secretion	J:129843
	disorganized pancreatic islets	J:129843
	impaired glucose tolerance	J:129843

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24