Nlrp1a Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nlrp1a
NLR family, pyrin domain containing 1A
MGI:2684861

17 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Casp1^tm1Sesh/Casp1^tm1Sesh Nlrp1a^Neut1/Nlrp1a^Neut1 involves: 129S2/SvPas * C57BL/6	normal immune system phenotype	J:191055
	increased circulating interleukin-18 level	J:191055
Cd3e^tm1Mal/Cd3e^tm1Mal Nlrp1a^Neut1/Nlrp1a^Neut1 involves: C57BL/6	increased neutrophil cell number	J:191055
	increased susceptibility to infection induced morbidity/mortality	J:191055
	skin inflammation	J:191055
Ifng^tm1Ts/Ifng^tm1Ts Nlrp1a^Neut1/Nlrp1a^Neut1 involves: 129S7/SvEvBrd * C57BL/6	brain inflammation	J:191055
	normal immune system phenotype	J:191055
Ighm^tm1Cgn/Ighm^tm1Cgn Nlrp1a^Neut1/Nlrp1a^Neut1 involves: 129S2/SvPas * C57BL/6	normal immune system phenotype	J:191055
Il1a^tm1Yiw/Il1a^tm1Yiw Nlrp1a^Neut1/Nlrp1a^Neut1 involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal inflammatory response	J:191055
	increased neutrophil cell number	J:191055
Il1r1^tm1Roml/Il1r1^tm1Roml Nlrp1a^Neut1/Nlrp1a^Neut1 involves: 129S1/Sv * C57BL/6	abnormal leukocyte cell number	J:191055
	abnormal leukopoiesis	J:191055
	decreased eosinophil cell number	J:191055
	decreased lymphocyte cell number	J:191055
	decreased monocyte cell number	J:191055
	normal immune system phenotype	J:191055
	increased susceptibility to Riboviria infection	J:191055
	increased susceptibility to xenobiotic induced morbidity/mortality	J:191055
	thrombocytopenia	J:191055
Il18^tm1Aki/Il18^tm1Aki Nlrp1a^Neut1/Nlrp1a^Neut1 involves: 129P2/OlaHsd * C57BL/6	abnormal inflammatory response	J:191055
	increased neutrophil cell number	J:191055
	myocarditis	J:191055
	premature death	J:191055
Nlrp1a^Neut1/Nlrp1a^Neut1 Pycard^tm1Vmd/Pycard^tm1Vmd involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal inflammatory response	J:191055
	increased neutrophil cell number	J:191055

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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