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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nlrp1a
NLR family, pyrin domain containing 1A
MGI:2684861
17 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Casp1tm1Sesh/Casp1tm1Sesh
Nlrp1aNeut1/Nlrp1aNeut1
involves: 129S2/SvPas * C57BL/6 		normal immune system phenotype J:191055
increased circulating interleukin-18 level J:191055
Cd3etm1Mal/Cd3etm1Mal
Nlrp1aNeut1/Nlrp1aNeut1
involves: C57BL/6 		increased neutrophil cell number J:191055
increased susceptibility to infection induced morbidity/mortality J:191055
skin inflammation J:191055
Ifngtm1Ts/Ifngtm1Ts
Nlrp1aNeut1/Nlrp1aNeut1
involves: 129S7/SvEvBrd * C57BL/6 		brain inflammation J:191055
normal immune system phenotype J:191055
Ighmtm1Cgn/Ighmtm1Cgn
Nlrp1aNeut1/Nlrp1aNeut1
involves: 129S2/SvPas * C57BL/6 		normal immune system phenotype J:191055
Il1atm1Yiw/Il1atm1Yiw
Nlrp1aNeut1/Nlrp1aNeut1
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal inflammatory response J:191055
increased neutrophil cell number J:191055
Il1r1tm1Roml/Il1r1tm1Roml
Nlrp1aNeut1/Nlrp1aNeut1
involves: 129S1/Sv * C57BL/6 		abnormal leukocyte cell number J:191055
abnormal leukopoiesis J:191055
decreased eosinophil cell number J:191055
decreased lymphocyte cell number J:191055
decreased monocyte cell number J:191055
normal immune system phenotype J:191055
increased susceptibility to Riboviria infection J:191055
increased susceptibility to xenobiotic induced morbidity/mortality J:191055
thrombocytopenia J:191055
Il18tm1Aki/Il18tm1Aki
Nlrp1aNeut1/Nlrp1aNeut1
involves: 129P2/OlaHsd * C57BL/6 		abnormal inflammatory response J:191055
increased neutrophil cell number J:191055
myocarditis J:191055
premature death J:191055
Nlrp1aNeut1/Nlrp1aNeut1
Pycardtm1Vmd/Pycardtm1Vmd
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal inflammatory response J:191055
increased neutrophil cell number J:191055
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
07/02/2024
MGI 6.13 		The Jackson Laboratory