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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cpap
centrosome assembly and centriole elongation protein
MGI:2684927
82 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cpaptm1.1Tkt/Cpaptm1.1Tkt
Not Specified 		embryonic lethality between somite formation and embryo turning, complete penetrance J:184889
Cpaptm1a(EUCOMM)Wtsi/Cpaptm1a(EUCOMM)Wtsi
B6Brd;B6N-Tyrc-Brd Cpaptm1a(EUCOMM)Wtsi/Wtsi 		abnormal caudal vertebrae morphology J:194085
abnormal cell physiology J:194085
abnormal ciliary process morphology J:194085
abnormal cornea endothelium morphology J:194085
abnormal deltoid tuberosity morphology J:194085
abnormal dentate gyrus morphology J:194085
abnormal Descemet membrane morphology J:194085
abnormal double-strand DNA break repair J:194085
abnormal glucose tolerance J:194085
abnormal humerus morphology J:194085
abnormal intramembranous bone ossification J:194085
abnormal iridocorneal angle J:194085
abnormal iris morphology J:194085
abnormal joint morphology J:194085
abnormal mitosis J:194085
abnormal mitotic spindle morphology J:194085
abnormal myocardial fiber morphology J:194085
abnormal occipital bone morphology J:194085
abnormal parietal bone morphology J:194085
abnormal pelvic girdle bone morphology J:194085
abnormal retina photoreceptor layer morphology J:194085
abnormal social investigation J:194085
abnormal sternocostal joint morphology J:194085
abnormal thoracic cage morphology J:194085
abnormal vertebrae morphology J:194085
anophthalmia J:194085
normal behavior/neurological phenotype J:194085
bowed humerus J:194085
caudal vertebral fusion J:194085
normal cellular phenotype J:194085
chromosomal instability J:194085
decreased body length J:194085
decreased body size J:194085
decreased body weight J:194085
decreased brain weight J:194085
decreased circulating serum albumin level J:194085
decreased cranium length J:194085
decreased fetal size J:194085
decreased fetal weight J:194085
decreased inner canthal distance J:194085
decreased neuron number J:194085
delayed sexual maturation J:194085
eyelids fail to open J:194085
increased CD8-positive, alpha-beta T cell number J:194085
increased embryonic tissue cell apoptosis J:194085
increased T cell number J:194085
iris synechia J:194085
lethality throughout fetal growth and development, incomplete penetrance J:194085
normal nervous system phenotype J:194085
polysyndactyly J:194085
postnatal growth retardation J:194085
prenatal growth retardation J:194085
retention of the adrenal gland x-zone J:194085
short lumbar vertebrae J:194085
sloping forehead J:194085
small cranium J:194085
small sacral vertebrae J:194085
normal taste/olfaction phenotype J:194085
Cpaptm1a(EUCOMM)Wtsi/Cpaptm1a(EUCOMM)Wtsi
B6JTyr;B6N-Cpaptm1a(EUCOMM)Wtsi/Wtsi 		abnormal behavior J:175295
abnormal cranium morphology J:175295
abnormal external male genitalia morphology J:175295
abnormal femur morphology J:175295
abnormal head morphology J:175295
abnormal humerus morphology J:175295
abnormal joint morphology J:175295
abnormal tail morphology J:175295
abnormal tail movements J:175295
abnormal tibia morphology J:175295
abnormal ulna morphology J:175295
abnormal vertebrae morphology J:175295
decreased body length J:175295
decreased body weight J:175295
decreased bone mineral content J:175295
decreased circulating calcium level J:175295
decreased circulating serum albumin level J:175295
decreased circulating total protein level J:175295
decreased lean body mass J:175295
decreased locomotor activity J:175295
decreased total body fat amount J:175295
increased sacral vertebrae number J:175295
vertebral fusion J:175295
Cpaptm1b(EUCOMM)Wtsi/Cpaptm1b(EUCOMM)Wtsi
involves: C57BL/6 * C57BL/6N * FVB/NJ 		abnormal embryo development J:208632
embryonic growth arrest J:208632
embryonic lethality during organogenesis, complete penetrance J:208632
Cpaptm1d(EUCOMM)Wtsi/Cpaptm1c(EUCOMM)Wtsi
Tg(Zp3-cre)93Knw/0
involves: C57BL/6J * C57BL/6N * FVB/NJ 		abnormal embryo development J:208632
embryonic growth arrest J:208632
embryonic lethality during organogenesis, complete penetrance J:208632
Cpaptm1d(EUCOMM)Wtsi/Cpaptm1d(EUCOMM)Wtsi
involves: C57BL/6 * C57BL/6N * FVB/NJ 		abnormal centrosome morphology J:208632
abnormal embryo turning J:208632
abnormal mitosis J:208632
absent embryonic cilia J:208632
embryonic growth arrest J:208632
embryonic lethality during organogenesis, complete penetrance J:208632
increased embryonic tissue cell apoptosis J:208632
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
MGI 6.24 		The Jackson Laboratory