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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Myrf
myelin regulatory factor
MGI:2684944
25 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Myrfem1(IMPC)Bay/Myrf+
C57BL/6N-Myrfem1(IMPC)Bay/BayMmucd 		abnormal embryo size J:211773
embryonic growth retardation J:211773
increased cornea thickness J:211773
Myrfem1(IMPC)Bay/Myrfem1(IMPC)Bay
C57BL/6N-Myrfem1(IMPC)Bay/BayMmucd 		abnormal embryo size J:211773
abnormal embryo turning J:211773
embryonic growth retardation J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Myrftm1Barr/Myrf+
Tg(rx3-icre)1Mjam/0
involves: 129P2/OlaHsd * C57BL/6J 		retina degeneration J:275842
retina pigment epithelium atrophy J:275842
Myrftm1Barr/Myrftm1.1Barr
Tg(rx3-icre)1Mjam/0
involves: 129P2/OlaHsd * C57BL/6J 		abnormal retina pigmentation J:275842
Myrftm1Barr/Myrftm1Barr
Cnptm1(cre)Kan/Cnp+
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 		abnormal myelination J:150563
abnormal oligodendrocyte morphology J:150563
abnormal spinal cord morphology J:150563
postnatal lethality, complete penetrance J:150563
seizures J:150563
tremors J:150563
Myrftm1Barr/Myrftm1Barr
Olig2tm2(TVA,cre)Rth/Olig2+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 		abnormal myelination J:150563
abnormal optic nerve morphology J:150563
abnormal spinal cord morphology J:150563
ataxia J:150563
normal nervous system phenotype J:150563
postnatal lethality, complete penetrance J:150563
seizures J:150563
tremors J:150563
Myrftm1Barr/Myrftm1Barr
Tg(rx3-icre)1Mjam/0
involves: 129P2/OlaHsd * C57BL/6J 		abnormal cone electrophysiology J:275842
abnormal retina pigmentation J:275842
abnormal rod electrophysiology J:275842
decreased retina cone cell number J:275842
decreased total retina thickness J:275842
retina degeneration J:275842
retina pigment epithelium atrophy J:275842
short photoreceptor inner segment J:275842
short photoreceptor outer segment J:275842
thin retina outer nuclear layer J:275842
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory