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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gmnc
geminin coiled-coil domain containing
MGI:2685452
34 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gmnctm1.1Strc/Gmnctm1.1Strc
involves: C57BL/6 * CBA 		abnormal brain morphology J:231675
abnormal motile cilium morphology J:231675
abnormal nasal mucosa goblet cell morphology J:231675
abnormal respiratory epithelium morphology J:231675
abnormal seminiferous tubule morphology J:231675
abnormal spermatid morphology J:231675
abnormal spermatogenesis J:231675
abnormal tertiary ovarian follicle morphology J:231675
abnormal tracheal ciliated epithelium morphology J:231675
absent brain ependyma motile cilia J:231675
absent oviduct epithelium motile cilium J:231675
absent respiratory motile cilia J:231675
azoospermia J:231675
decreased body weight J:231675
decreased primordial ovarian follicle number J:231675
decreased secondary ovarian follicle number J:231675
decreased survivor rate J:231675
dilated brain ventricle J:231675
dilated lateral ventricle J:231675
dilated third ventricle J:231675
female infertility J:231675
hippocampus atrophy J:231675
hydrocephaly J:231675
increased cell death J:231675
increased respiratory mucosa goblet cell number J:231675
male infertility J:231675
ovary degeneration J:231675
postnatal growth retardation J:231675
small ovary J:231675
small oviduct J:231675
Gmnctm1a(KOMP)Wtsi/Gmnctm1a(KOMP)Wtsi
involves: C57BL/6N 		abnormal tracheal ciliated epithelium morphology J:230806
absent respiratory motile cilia J:230806
increased respiratory mucosa goblet cell number J:230806
postnatal growth retardation J:230806
postnatal lethality, complete penetrance J:230806
slow postnatal weight gain J:230806
Gmnctm1b(KOMP)Wtsi/Gmnc+
C57BL/6N-Gmnctm1b(KOMP)Wtsi/Wtsi 		increased circulating sodium level J:211773
increased grip strength J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory