Wdtc1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Wdtc1
WD and tetratricopeptide repeats 1
MGI:2685541

20 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Fabp4-Wdct1*)1Jmgr/? involves: ICR	abnormal white adipose tissue morphology	J:129966
	increased circulating glucose level	J:129966
	increased fat cell size	J:129966
	increased total body fat amount	J:129966
Tg(Fabp4-Wdtc1)1Jmgr/? involves: ICR	abnormal fat cell morphology	J:129966
	decreased body weight	J:129966
	decreased circulating glucose level	J:129966
	decreased circulating insulin level	J:129966
	decreased circulating leptin level	J:129966
	decreased total body fat amount	J:129966
	increased insulin sensitivity	J:129966
Wdtc1^{Gt(RRF015)Byg}/Wdtc1⁺ involves: 129P2/OlaHsd * ICR	increased circulating glucose level	J:129966
	increased circulating insulin level	J:129966
	increased circulating leptin level	J:129966
	increased fat cell size	J:129966
	insulin resistance	J:129966
	obese	J:129966
Wdtc1^{Gt(RRF015)Byg}/Wdtc1^{Gt(RRF015)Byg} involves: 129P2/OlaHsd * ICR	obese	J:129966
	prenatal lethality, incomplete penetrance	J:129966
Wdtc1^{tm1a(KOMP)Wtsi}/Wdtc1^{tm1a(KOMP)Wtsi} C57BL/6N-Wdtc1^{tm1a(KOMP)Wtsi}/Wtsi	abnormal vertebral arch morphology	J:211773
	decreased circulating HDL cholesterol level	J:211773
	decreased circulating LDL cholesterol level	J:211773
	decreased fasting circulating glucose level	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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