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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Opa3
optic atrophy 3
MGI:2686271
49 phenotypes from 1 allele in 1 genetic background
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Allelic Composition
Genetic Background		 Annotated Term Reference
Opa3m1Votr/Opa3m1Votr
involves: C3H * C57BL/6JCrl 		abnormal abdominal fat pad morphology J:181670
abnormal blood homeostasis J:188346
abnormal brown adipose tissue morphology J:188346
abnormal epiphyseal plate morphology J:188346
abnormal gait J:181670
abnormal heart left ventricle morphology J:181670
abnormal liver morphology J:181670
abnormal long bone epiphyseal plate proliferative zone J:188346
abnormal mitochondrial morphology J:181670
abnormal mitochondrial physiology J:181670, J:188346
abnormal optic nerve morphology J:181670
abnormal phospholipid level J:188346
abnormal pilomotor reflex J:181670
abnormal retina layer morphology J:181670
abnormal retina nerve fiber layer morphology J:181670
abnormal ventricle myocardium morphology J:181670
abnormal vision J:181670
abnormal white adipose tissue morphology J:188346
axon degeneration J:181670
cardiac interstitial fibrosis J:181670
decreased birth body size J:181670
decreased body length J:188346
decreased body surface temperature J:188346
decreased body weight J:181670, J:188346
decreased circulating insulin-like growth factor I level J:188346
decreased fat cell size J:188346
decreased liver glycogen level J:181670
decreased locomotor activity J:181670
decreased retina ganglion cell number J:181670
decreased total body fat amount J:181670
decreased white adipose tissue amount J:188346
dehydration J:181670
dilated cardiomyopathy J:181670
dilated heart left ventricle J:181670
dilated heart right ventricle J:181670
hunched posture J:181670
increased brown adipose tissue amount J:188346
increased liver triglyceride level J:188346
increased liver weight J:188346
macrovesicular hepatic steatosis J:188346
postnatal growth retardation J:181670, J:188346
premature death J:181670
preweaning lethality, incomplete penetrance J:181670
short snout J:181670
thin interventricular septum J:181670
thin retina ganglion layer J:181670
thin retina inner plexiform layer J:181670
thin retina outer nuclear layer J:181670
tremors J:181670
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory