Kash5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kash5
KASH domain containing 5
MGI:2687329

23 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kash5^em1(IMPC)J/Kash5^em1(IMPC)J C57BL/6NJ-Kash5^em1(IMPC)J/Mmjax	abnormal bone structure	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased lean body mass	J:211773
	decreased locomotor activity	J:211773
	female infertility	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased leukocyte cell number	J:211773
	increased total body fat amount	J:211773
	male infertility	J:211773
Kash5^{tm1b(KOMP)Wtsi}/Kash5^{tm1b(KOMP)Wtsi} involves: C57BL/6J * C57BL/6N	abnormal chromosomal synapsis	J:201813
	abnormal double-strand DNA break repair	J:201813
	abnormal meiotic attachment of telomere to nuclear envelope	J:201813
	abnormal oogenesis	J:201813
	abnormal seminiferous tubule morphology	J:201813
	abnormal spermatocyte morphology	J:201813
	absent ovarian follicles	J:201813
	arrest of male meiosis	J:201813
	decreased male germ cell number	J:201813
	female infertility	J:201813
	increased testis apoptosis	J:201813
	male infertility	J:201813
	small ovary	J:201813
	small seminiferous tubules	J:201813
	small testis	J:201813

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24