Zc3h12c Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Zc3h12c
zinc finger CCCH type containing 12C
MGI:3026959

26 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Zc3h12c^em1(IMPC)Tcp/Zc3h12c^em1(IMPC)Tcp C57BL/6NCrl-Zc3h12c^em1(IMPC)Tcp/Tcp	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased lymphocyte cell number	J:211773
	enlarged lymph nodes	J:211773
	increased circulating triglyceride level	J:211773
	increased neutrophil cell number	J:211773
Zc3h12c^{tm2c(EUCOMM)Hmgu}/Zc3h12c^{tm2c(EUCOMM)Hmgu} Cd19^tm1(cre)Cgn/Cd19⁺ involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N	normal immune system phenotype	J:277714
Zc3h12c^{tm2c(EUCOMM)Hmgu}/Zc3h12c^{tm2c(EUCOMM)Hmgu} Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N	enlarged lymph nodes	J:277714
	increased B cell number	J:277714
	increased CD4-positive, alpha-beta T cell number	J:277714
	increased effector memory CD8-positive, alpha-beta T cell number	J:277714
	increased immature B cell number	J:277714
	increased marginal zone B cell number	J:277714
Zc3h12c^{tm2c(EUCOMM)Hmgu}/Zc3h12c^{tm2c(EUCOMM)Hmgu} Tg(Cd4-cre)1Cwi/0 involves: 129S4/SvJaeSor * C57BL/6N * DBA/2	normal immune system phenotype	J:277714
Zc3h12c^{tm2d(EUCOMM)Hmgu}/Zc3h12c^{tm2d(EUCOMM)Hmgu} involves: 129S4/SvJaeSor * C57BL/6N	abnormal lymph node cortex morphology	J:277714
	abnormal lymph node primary follicle morphology	J:277714
	decreased CD8-positive, alpha-beta T cell number	J:277714
	decreased germinal center B cell number	J:277714
	decreased macrophage cell number	J:277714
	enlarged lymph nodes	J:277714
	extramedullary hematopoiesis	J:277714
	normal immune system phenotype	J:277714
	increased B cell number	J:277714
	increased CD4-positive, alpha-beta T cell number	J:277714
	increased circulating interferon-gamma level	J:277714
	increased effector memory CD4-positive, alpha-beta T cell number	J:277714
	increased IgA level	J:277714
	increased IgG level	J:277714
	increased IgM level	J:277714
	increased immature B cell number	J:277714
	increased marginal zone B cell number	J:277714
	increased myeloid cell number	J:277714
	increased splenocyte number	J:277714
	increased T cell number	J:277714

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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