Nlrc4 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nlrc4
NLR family, CARD domain containing 4
MGI:3036243

6 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Del(13Naip1-Naip5)1Vnce/Del(13Naip1-Naip5)1Vnce Nlrc4^em2Vnce/Nlrc4^em2Vnce involves: C57BL/6	decreased inflammatory response	J:294930
	decreased lactate dehydrogenase level	J:294930
Gt(ROSA)26Sor^{tm1(OVAL/fla,GFP)Vnce}/Gt(ROSA)26Sor⁺ Lyz2^tm1(cre)Ifo/Lyz2⁺ Nlrc4^tm1Vmd/Nlrc4^tm1Vmd involves: 129P2/OlaHsd * C57BL/6J * C57BL/6NCrl	normal immune system phenotype	J:260047
	normal skeleton phenotype	J:260047
Nlrc4^em1Vnce/Nlrc4^em1Vnce Nlrp3^tm1Vmd/Nlrp3^tm1Vmd involves: C57BL/6J * C57BL/6N	decreased inflammatory response	J:294930
	decreased lactate dehydrogenase level	J:294930
Nlrc4^em2Vnce/Nlrc4^em2Vnce Nlrp3^tm1Vmd/Nlrp3^tm1Vmd involves: C57BL/6J * C57BL/6N	decreased inflammatory response	J:294930
	decreased lactate dehydrogenase level	J:294930
Nlrc4^tm1Gln/Nlrc4^tm1Gln Slc11a1^s/Slc11a1^s B6.129S5-Nlrc4^tm1Gln	increased susceptibility to bacterial infection	J:124378
Nlrc4^tm1Vmd/Nlrc4^tm1Vmd Nlrp3^tm1Vmd/Nlrp3^tm1Vmd C57BL/6-Nlrp3^tm1Vmd Nlrc4^tm1Vmd	decreased interleukin-1 beta secretion	J:160545

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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