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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Duox2
dual oxidase 2
MGI:3036280
48 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Duox2em1(IMPC)Mbp/Duox2em1(IMPC)Mbp
C57BL/6N-Duox2em1(IMPC)Mbp/MbpMmucd 		abnormal heart morphology J:211773
abnormal kidney morphology J:211773
abnormal liver morphology J:211773
abnormal lymph node morphology J:211773
abnormal spleen morphology J:211773
decreased exploration in new environment J:211773
decreased grip strength J:211773
decreased heart weight J:211773
decreased lymphocyte cell number J:211773
decreased prepulse inhibition J:211773
enlarged lymph nodes J:211773
enlarged spleen J:211773
female infertility J:211773
increased circulating calcium level J:211773
increased circulating cholesterol level J:211773
increased circulating creatinine level J:211773
increased circulating HDL cholesterol level J:211773
increased circulating serum albumin level J:211773
increased circulating total protein level J:211773
increased fasting circulating glucose level J:211773
increased freezing behavior J:211773
increased mean corpuscular volume J:211773
increased neutrophil cell number J:211773
small heart J:211773
small kidney J:211773
small liver J:211773
small spleen J:211773
Duox2em1Btlr/Duox2em1Btlr
C57BL/6J-Duox2em1Btlr/Btlr 		decreased body size J:309727
short femur J:309727
short tibia J:309727
small pubis J:309727
Duox2m1Btlr/Duox2m1Btlr
C57BL/6J-Duox2m1Btlr/Btlr 		decreased body size J:309727
short femur J:309727
short tibia J:309727
small pubis J:309727
Duox2thyd/Duox2thyd
B6(129)-Duox2thyd/J 		abnormal adenohypophysis morphology J:121821
abnormal bone mineralization involved in bone maturation J:121821
abnormal tectorial membrane morphology J:121821
abnormal thyroid follicle morphology J:121821
decreased activity of thyroid gland J:121821
decreased areal bone mineral density J:121821
decreased body size J:121821
decreased body weight J:121821
decreased bone mineral density J:121821
decreased circulating insulin-like growth factor I level J:121821
decreased circulating thyroxine level J:121821
decreased percent body fat/body weight J:121821
delayed inner ear development J:121821
increased circulating thyroid-stimulating hormone level J:121821
increased or absent threshold for auditory brainstem response J:121821
infertility J:121821
normal skeleton phenotype J:121821
thyroid gland hyperplasia J:121821
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory