Cerkl Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cerkl
ceramide kinase-like
MGI:3037816

26 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cerkl^em1Gmar/Cerkl^em1Gmar involves: C57BL/6J	embryonic lethality, complete penetrance	J:292626
Cerkl^em1Gmar/Cerkl^tm1.1Geno involves: 129 * C57BL/6J	abnormal cone electrophysiology	J:292626
	abnormal electroretinogram waveform feature	J:292626
	abnormal photoreceptor outer segment disc membrane morphology	J:292626
	abnormal retina cone cell morphology	J:292626
	abnormal retina ganglion cell morphology	J:292626
	abnormal retina outer nuclear layer morphology	J:292626
	abnormal retina pigment epithelium morphology	J:292626
	abnormal retina rod cell outer segment morphology	J:292626
	abnormal rod electrophysiology	J:292626
	abnormal total retina thickness	J:292626
	abnormal vision	J:292626
	cataract	J:292626
	decreased b-wave amplitude	J:292626
	decreased retina photoreceptor cell number	J:292626
	disorganized photoreceptor outer segment	J:292626
	disorganized retina layers	J:292626
	increased susceptibility to age-related retinal degeneration	J:292626
	long photoreceptor outer segment	J:292626
	retina cone cell degeneration	J:292626
	retina gliosis	J:292626
	thin retina outer nuclear layer	J:292626
Cerkl^tm1.1Geno/Cerkl^tm1.1Geno involves: 129 * C57BL/6J	abnormal eye electrophysiology	J:185135
Cerkl^tm1.1Geno/Cerkl^tm1.1Geno involves: 129 * C57BL/6J	increased retina apoptosis	J:185135
Cerkl^tm1.1Npa/Cerkl^tm1.1Npa involves: BALB/c	normal vision/eye phenotype	J:137892
Cerkl^{tm1b(KOMP)Wtsi}/Cerkl^{tm1b(KOMP)Wtsi} C57BL/6N-Cerkl^{tm1b(KOMP)Wtsi}/Ieg	decreased exploration in new environment	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24