B3gnt6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

B3gnt6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
MGI:3039603

22 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
B3gnt6^tm1Lx/B3gnt6^tm1Lx involves: 129S1/Sv * C57BL/6J	abnormal crypts of Lieberkuhn morphology	J:123826
	abnormal enterocyte proliferation	J:123826
	abnormal intestinal mucosa morphology	J:123826
	decreased colon length	J:123826
	diarrhea	J:123826
	increased adenocarcinoma incidence	J:123826
	increased carcinoma incidence	J:123826
	increased gastrointestinal tumor incidence	J:123826
	increased incidence of tumors by chemical induction	J:123826
	increased interferon-gamma secretion	J:123826
	increased interleukin-2 secretion	J:123826
	increased intestinal adenoma incidence	J:123826
	increased macrophage cell number	J:123826
	increased monocyte cell number	J:123826
	increased susceptibility to induced colitis	J:123826
	increased susceptibility to weight loss	J:123826
	increased susceptibility to xenobiotic induced morbidity/mortality	J:123826
	increased T cell number	J:123826
	increased tumor growth/size	J:123826
	increased tumor necrosis factor secretion	J:123826
	intestinal ulcer	J:123826
	rectal hemorrhage	J:123826

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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