Znrf3 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Znrf3
zinc and ring finger 3
MGI:3039616

4 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Rnf43^tm1Cle/Rnf43^tm1Cle Znrf3^tm1Cle/Znrf3^tm1Cle Lgr5^{tm1(cre/ERT2)Cle}/Lgr5⁺ involves: 129P2/OlaHsd	increased intestinal adenoma incidence	J:186765
Rnf43^tm1Cle/Rnf43^tm1Cle Znrf3^tm1Cle/Znrf3^tm1Cle Tg(Vil1-cre/ERT2)23Syr/0 involves: C57BL/6 * DBA/2	abnormal small intestinal crypt cell proliferation	J:186765
	abnormal small intestine crypts of Lieberkuhn morphology	J:186765
	increased intestinal adenoma incidence	J:186765
	increased Paneth cell number	J:186765

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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