Vtcn1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vtcn1
V-set domain containing T cell activation inhibitor 1
MGI:3039619

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
H2^g7/H2^g7 Tg(Ins2-Vtcn1)#Xxz/0 Tg(TcraBDC2.5,TcrbBDC2.5)1Doi/0 involves: C57BL/6 * NOD * SJL	decreased interferon-gamma secretion	J:177612
	decreased interleukin-17 secretion	J:177612
	decreased regulatory T cell number	J:177612
	decreased susceptibility to autoimmune diabetes	J:177612
Rag1^tm1Mom/Rag1^tm1Mom Vtcn1^tm1Lpc/Vtcn1^tm1Lpc involves: 129S/SvEvBrd * 129S7/SvEvBrd * C57BL/6	abnormal neutrophil differentiation	J:145712
	decreased susceptibility to bacterial infection	J:145712
	decreased susceptibility to bacterial infection induced morbidity/mortality	J:145712
	increased neutrophil cell number	J:145712
	increased spleen weight	J:145712

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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