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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ticam2
TIR domain containing adaptor molecule 2
MGI:3040056
6 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ticam2M1Btlr/Ticam2+
C57BL/6J-Ticam2M1Btlr 		decreased tumor necrosis factor secretion J:215010
Ticam2M1Btlr/Ticam2M1Btlr
C57BL/6J-Ticam2M1Btlr 		decreased tumor necrosis factor secretion J:215010
Ticam2M2Btlr/Ticam2+
C57BL/6J-Ticam2M2Btlr 		decreased interleukin-1 beta secretion J:254908
Ticam2M2Btlr/Ticam2M2Btlr
C57BL/6J-Ticam2M2Btlr 		decreased interleukin-1 beta secretion J:254908
Ticam2M3Btlr/Ticam2+
C57BL/6J-Ticam2M3Btlr 		decreased tumor necrosis factor secretion J:254912
Ticam2M3Btlr/Ticam2M3Btlr
C57BL/6J-Ticam2M3Btlr 		decreased tumor necrosis factor secretion J:254912
Ticam2tm1Aki/Ticam2tm1Aki
involves: C57BL/6 		abnormal immune system physiology J:86256
decreased interleukin-6 secretion J:86256
increased susceptibility to Coronaviridae infection J:270045
Ticam2tm1Btlr/Ticam2tm1Btlr
C57BL/6J-Ticam2tm1Btlr 		abnormal interferon secretion J:133619
decreased tumor necrosis factor secretion J:133619
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory