Zmiz1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Zmiz1
zinc finger, MIZ-type containing 1
MGI:3040693

25 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Mx1-cre)1Cgn/0 Zmiz1^{tm1c(EUCOMM)Hmgu}/Zmiz1^{tm1c(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA/J	decreased B cell number	J:234445
	decreased incidence of induced tumors	J:234445
	decreased NK cell number	J:234445
	decreased T cell number	J:234445
	increased ileal goblet cell number	J:234445
	thymus hypoplasia	J:234445
Tg(Vil1-cre/ERT2)23Syr/0 Zmiz1^{tm1c(EUCOMM)Hmgu}/Zmiz1^{tm1c(EUCOMM)Hmgu} involves: C57BL/6 * C57BL/6N * DBA/2	normal digestive/alimentary phenotype	J:234445
Zmiz1^tm1Zsu/Zmiz1⁺ involves: 129S6/SvEvTac * C57BL/6J	preweaning lethality, incomplete penetrance	J:128915
Zmiz1^tm1Zsu/Zmiz1^tm1Zsu involves: 129S6/SvEvTac * C57BL/6J	abnormal capillary morphology	J:128915
	abnormal dorsal aorta morphology	J:128915
	abnormal heart atrium morphology	J:128915
	abnormal heart valve morphology	J:128915
	abnormal perineural vascular plexus morphology	J:128915
	abnormal pharyngeal arch artery morphology	J:128915
	abnormal vascular branching morphogenesis	J:128915
	abnormal vascular development	J:128915
	abnormal vitelline vascular remodeling	J:128915
	abnormal vitelline vasculature morphology	J:128915
	decreased cell proliferation	J:128915
	decreased embryo size	J:128915
	dilated dorsal aorta	J:128915
	embryonic lethality during organogenesis, complete penetrance	J:128915
	normal hematopoietic system phenotype	J:128915
	pale yolk sac	J:128915
	pallor	J:128915

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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