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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Palb2
partner and localizer of BRCA2
MGI:3040695
9 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cdkn1atm1Tyj/Cdkn1atm1Tyj
Palb2tm1.2Dli/Palb2tm1.2Dli
involves: 129S2/SvPas * 129S4/SvJaeSor * BALB/cJ * C57BL/6 		abnormal embryo development J:197442
fetal growth retardation J:197442
lethality throughout fetal growth and development, complete penetrance J:197442
Palb2tm1.1Dli/Palb2tm1.1Dli
Trp53tm1Brn/Trp53+
Tg(KRT14-cre)1Amc/0
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CBA 		decreased tumor latency J:197442
increased mammary gland tumor incidence J:197442
Palb2tm1.1Dli/Palb2tm1.1Dli
Trp53tm1Brn/Trp53tm1Brn
Tg(KRT14-cre)1Amc/0
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * CBA 		abnormal tumor morphology J:197442
decreased tumor latency J:197442
increased mammary gland tumor incidence J:197442
increased mouth tumor incidence J:197442
increased skin tumor incidence J:197442
Palb2tm1.1Dli/Palb2tm1.1Dli
Trp53bp1tm1Jc/Trp53bp1tm1Jc
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 		chromosome breakage J:197442
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory