Prex1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
MGI:3040696

15 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prex1^tm1Dwu/Prex1^tm1Dwu Not Specified	impaired neutrophil chemotaxis	J:102213
Prex1^tm1Hcew/Prex1^tm1Hcew involves: 129P2/OlaHsd	normal behavior/neurological phenotype	J:133335
Prex1^tm1Hcew/Prex1^tm1Hcew involves: 129P2/OlaHsd	normal nervous system phenotype	J:133335
Prex1^tm1Hcew/Prex1^tm1Hcew involves: 129P2/OlaHsd * C57BL/6	abnormal contextual conditioning behavior	J:228203
	abnormal learning/memory/conditioning	J:228203
	abnormal social investigation	J:228203
	normal behavior/neurological phenotype	J:228203
	decreased body weight	J:102214, J:228203
	decreased vocalization	J:228203
	impaired neutrophil chemotaxis	J:102214
	impaired neutrophil recruitment	J:102214
	impaired spatial learning	J:228203
	increased grooming behavior	J:228203
	increased neutrophil cell number	J:102214
	normal nervous system phenotype	J:228203
	reduced long-term depression	J:228203
	small liver	J:102214
	normal taste/olfaction phenotype	J:228203

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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